The Johns Hopkins School of Medicine’s Brain Science Institute (BSi) brings together both basic and clinical neuroscientists from across the Johns Hopkins campuses. The Johns Hopkins Drug Discovery (JHDD) program was originally established as part of the BSi with the mission of translating basic sciences arising from JHU neuroscience community into novel therapeutics for neurological disorders.. While JHDD’s mission has expanded to other therapeutic areas, our program continues to be engaged in neurotherapeutics development through collaborations fostered by BSi.