2024 » Johns Hopkins Drug Discovery
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2024

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248. Chen J, Yang J, Chu J, Hong Chen K, Alt J, Rais R, Qiu Z, “The SWELL1 Channel Promotes Ischemic Brain Damage by Mediating Neuronal Swelling and Glutamate Toxicity,” Advanced Science, 2024 [PubMed]

247. Novotná K, Tenora L, Slusher BS, Rais R, “Therapeutic resurgence of 6-diazo-5-oxo-l-norleucine (DON) through tissue-targeted prodrugs,” Advances in Pharmacology, 2024 [PubMed]

246. Praharaj M, Shen F, Lee AJ, Zhao L, Nirschl TR, Theodros D, Singh AK, Wang X, Adusei KM, Lombardo KA, Williams RA, Sena LA, Thompson EA, Tam A, Yegnasubramanian S, Pearce EJ, Leone RD, Alt J, Rais R, Slusher BS, Pardoll DM, Powell JD, Zarif JC. “Metabolic reprogramming of tumor-associated macrophages using glutamine antagonist JHU083 drives tumor immunity in myeloid-rich prostate 239. and bladder cancer tumors,” Cancer Immunology Research, 2024 [PubMed]

245. Chen EC, Shapiro RL, Pal A, Bartee D, DeLong K, Carter DM, Serrano-Diaz E, Rais R, Ensign LM, Freel Meyers CL. “Investigating inhibitors of 1-deoxy-d-xylulose 5-phosphate synthase in a mouse model of UTI,” Microbiology Spectrum, 2024 [PubMed]

244. Peters DE, Brownlee M, Layne-Colon D, Slusher BS. “Discovery of PSMA in the prostate of the common marmoset (Callithrix jacchus),” The Prostrate, 2024 [PubMed

243. Ramos A, Ishizuka K, Hayashida A, Namkung H, Hayes LN, Srivastava R, Zhang M, Kariya T, Elkins N, Palen T, Carloni E, Tsujimura T, Calva C, Ikemoto S, Rais R, Slusher BS, Niwa M, Saito A, Saitoh T, Takimoto E, Sawa A. “Nuclear GAPDH in cortical microglia mediates cellular stress-induced cognitive inflexibility,” Molecular Psychiatry, 2024 [PubMed]

242. Bonifazi A, Ellenberger M, Farino ZJ, Aslanoglou D, Rais R, Pereira S, Mantilla-Rivas JO, Boateng CA, Eshleman AJ, Janowsky A, Hahn MK, Schwartz GJ, Slusher BS, Newman AH, Freyberg Z. “Development of novel tools for dissection of central versus peripheral dopamine D2-like receptor signaling in dysglycemia,” bioRxiv, 2023 [PubMed]

241. Wiseman RL, Bigos KL, Dastgheyb RM, Barker PB, Rubin LH, Slusher BS. “Brain N -acetyl-aspartyl-glutamate is associated with cognitive function in older virally suppressed people with HIV,” AIDS, 2024 [PubMed]

240. Mueller LG, Slusher BS, Tsukamoto T. “Empirical Analysis of Drug Targets for Nervous System Disorders,” ACS Chemical Neuroscience, 2024 [PubMed]

239. Okorom AV, Camacho-Hernandez GA, Salomon K, Lee KH, Ku TC, Cao J, Won SJ, Friedman J, Lam J, Paule J, Rais R, Klein B, Xi ZX, Shi L, Loland CJ, Newman AH “Modifications to 1-(4-(2-Bis(4-fluorophenyl)methyl)sulfinyl)alkyl Alicyclic Amines That Improve Metabolic Stability and Retain an Atypical DAT Inhibitor Profile,” Journal of Medicinal Chemistry, 2024 [PubMed]